Ta Dah!


Professor Griffiths, Foundation Professor of Dermatology at The University of Manchester, in the UK, began research on No7 Protect & Perfect Serum, using a 12-day patch-test trial that he had developed while working at the University of Michigan. He was a sceptic about the idea that cosmetic anti-ageing products might genuinely improve the skin, but researchers put No7 Protect & Perfect Serum to the test against trans-retinoic acid, the gold-standard, prescription-only treatment for reducing wrinkling in the skin. His results showed that No7 Protect & Perfect Serum improved aspects of photo-aged skin in a similar way to trans-retinoic acid; the first time that the performance of a cosmetic product had been demonstrated in this way.


When this research was reported on a BBC Horizon programme in March, the reaction was instant and unprecedented, prompting a significant sales increase overnight on boots.com and across Boots stores in the following weeks.


In March the full research was published in the British Journal of Dermatology.


No7 Protect & Perfect Intense Serum was also found to have genuine, long-term anti-ageing benefits in a further 12 -month clinical trial also conducted at The University of Manchester. The serum, which targets deeper lines and wrinkles, and which is aimed at the 35-45 year old customer, was found to promote structural repair in the skin. This change was demonstrated by observing the changes in the levels of fibrillin, a protein that plays a key role in keeping the skin firm and elastic. The fibrillin repair was associated with a clinical reduction in the appearance of wrinkles. This study proved to be another landmark for No7, putting a cosmetic product into blind testing for a year. Again, this research was published in the British Journal of Dermatology, in August 2009.


The experts at No7 developed a third, clinically proven serum, No7 Lift & Luminate Day & Night Serum, proven to tackle the three key signs of ageing in women aged 45 - 60, namely lines and wrinkles, the loss of firmness, and uneven skin tone such as age spots. This product put together the existing, well -proven ingredients from the No7 Protect & Perfect formula with new de-pigmentation actives in revolutionary new separate day and night formulations. A pioneering clinical trial was undertaken by one of the world’s leading experts in pigmentation, Professor Ortonne, Head of Dermatology, Hopital L’Archet in Nice. The serums were tested against 4% Hydroquinone, commonly regarded by dermatologists as the gold-standard topical treatment for hyper-pigmentation, and the trial provided clinical proof that the serum had the ability to lighten and shrink age spots.

Professor Ortonne commented: "The results are exceptional - better than any other cosmetic product I have tested for the fading of age spots, with similar performance to the gold standard prescription-only treatment after four months use."

“Extensive research has enabled us to develop this clinically proven serum, which works at a deeper level to restore youthful skin for women aged 60 and over. In addition to wrinkles, loss of firmness and uneven skin tone, post-menopausal skin can become persistently drier and less resilient and lack luminosity due to the decline in oestrogen levels. Our unique complexes and proven technologies combined with a highly effective No7 serum delivery system help tackle each of these issues head-on, leaving skin feeling and looking younger in just four weeks.”

Dr Mike Bell
Boots Skincare Scientific Advisor

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